suicidal attempt in bipolar disorder:low significance of comorbidity with opioid dependence

objectives: the relationship between suicidal attempt and opioid use disorder in patients with bipolar disorder (bd) is unknown. this study aimed at shedding some light on this issue. method:178 inpatients aged 18-65 with bd type i with or without opioid use disorders were face-to-face interviewed through the persian structured clinical interview for dsm-iv axis i disorders (scid-i), the global assessment of functioning (gaf) scale, and a questionnaire including demographic and some clinical factors. results:gender was the only demographic factor with a statistical significant difference between suicidal and non-suicidal bipolar patients. also, comorbidity with anxiety disorders and the type of index and current mood episodes were significantly different between the two groups (p<0.05). but after using a logistic regression analysis, the only statistical significant different factors (p<0.05) between the two groups were gender, comorbidity with anxiety disorders, and gaf. conclusion:opioid dependence comorbidity can not be considered as a risk factor for suicidal attempt in patients with bd.